Catheter-Based Therapies for Massive Pulmonary Embolism

Abstract 

Massive pulmonary embolism carries a high mortality rate as a result of right ventricular failure. In addition to anticoagulation, systemic thrombolysis is the standard first line of therapy for patients with life-threatening massive pulmonary embolism. Surgical embolectomy is often considered in patients with contraindications to receiving systemic thrombolysis or when thrombolysis has failed. Surgical embolectomy is not without inherent risk and limitations.Although there is a paucity of large clinical trials, available data suggests catheter-based treatment of massive pulmonary embolism restores hemodynamic stability and thus is an alternative to surgical therapy.

Abbreviations: FDA, Food and Drug Administration, PA, pulmonary artery, PE, pulmonary embolism, RV, right ventricular

Keywords: Massive pulmonary embolism, Percutaneous therapy, Thrombectomy